基于文献计量学的枳椇子研究现状与发展趋势分析*

作者：张 芹1，戴 霞2

单位：1.山东中医药大学中医学院，山东 济南 250355； 2.山东中医药大学健康学院，山东 济南 250355

引用：引用：张芹，戴霞.基于文献计量学的枳椇子研究现状与发展趋势分析[J].中医药导报,2025,31(12):240-247.

DOI：10.13862/j.cn43-1446/r.2025.12.038

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摘要：

目的：分析枳椇子研究现状、研究热点及发展趋势。方法：检索中国知网（CNKI）和Web of Science（WOS）核心合集数据库自1990年1月1日至2025年5月20日收录的枳椇子相关文献，应用CiteSpace（6.2.R3）和VOSviewer（1.6.20）等软件对已发表中文文献、英文文献的年发文量、作者、国家、机构和关键词等进行可视化分析。结果：共纳入文献560篇，其中中文文献434篇，英文文献126篇，枳椇子的年总发文量在波动中整体呈上升趋势。中文文献发文量最多的作者为嵇扬（12篇），英文文献发文量最多的作者为KAN J Q（6篇）。中国是英文文献发文量最多的国家。中文文献研究机构以武汉大学人民医院药学部为主，英文文献研究机构以西南大学（Southwest University）为主。收录中文文献最多的期刊是《中药材》，收录英文文献最多的期刊是International Journal of Biological Macromolecules。高被引文献显示，枳椇子的研究热点主要在化学成分、药理活性及临床试验等方面。结论：枳棋子的研究热点集中于其活性成分（特别是黄酮类）的药理实验与临床研究。未来研究需结合分子生物学技术（如组学分析）与肠道菌群调控机制，推动枳椇子在药食同源产品（如功能饮料、保健食品）中的创新应用。

关键词：枳椇子；文献计量学；药食同源；肠道菌群；CiteSpace；VOSviewer

Abstract：

Objective: To analyze the research status, hotspots and development trends in the field of Zhijuzi (Hoveniae Fructus seu Semen). Methods: Relevant literatures on Zhijuzi (Hoveniae Fructus seu Semen) published from January 1, 1990 to May 20, 2025 were retrieved from China National Knowledge Infrastructure (CNKI) and Web of Science (WOS) Core Collection databases. Software such as CiteSpace (6.2.R3) and VOSviewer (1.6.20) were used to conduct visualized analysis on the annual number of publications, authors, countries, institutions and keywords of published Chinese and english literatures. Results: A total of 560 literatures were included, among which 434 were Chinese literatures and 126 were english literatures. The total annual number of publications on Zhijuzi (Hoveniae Fructus seu Semen) showed an overall upward trend with fluctuations. The author with the largest number of publications in Chinese literatures was JI Yang (12 papers), while the author with the most publications in english literatures was KAN J Q (6 papers). China was the country with the highest number of publications in english literatures. The leading research institution for Chinese literatures was the Department of Pharmacy, Renmin Hospital of Wuhan University, and that for english literatures was Southwest University. The journal with the most included Chinese literatures was Journal of Chinese Medicinal Materials, and the journal with the most included English literatures was International Journal of Biological Macromolecules. Highly cited literatures indicated that the research hotspots of Zhijuzi (Hoveniae Fructus seu Semen) mainly focused on chemical components, pharmacological activities and clinical trials. Conclusion: The research hotspots of Zhijuzi (Hoveniae Fructus seu Semen) focus on the pharmacological experiments and clinical studies of its active components (especially flavonoids). Future research needs to combine molecular biology technologies (such as omics analysis) with intestinal flora regulation mechanisms to promote the innovative application of Zhijuzi (Hoveniae Fructus seu Semen) in medicine-food homology products (such as functional beverages and health food).

Key words：Zhijuzi (Hoveniae Fructus seu Semen); bibliometrics; medicine-food homology; intestinal flora; CiteSpace; VOSviewer

发布时间：2025-12-31

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