疏肝解郁汤联合中医走罐疗法治疗甲状腺结节的疗效观察*

作者：程超超，姚舒雅，王 静，何昌能，王 书

单位：合肥市第一人民医院，安徽 合肥 230061

引用：引用：程超超，姚舒雅，王静，何昌能，王书.疏肝解郁汤联合中医走罐疗法治疗甲状腺结节的疗效观察[J].中医药导报,2025,31(11):85-89.

DOI：10.13862/j.cn43-1446/r.2025.11.015

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摘要：

目的：探讨疏肝解郁汤联合中医走罐疗法治疗甲状腺结节的疗效。方法：纳入84例甲状腺结节患者，采用随机数字表法分为对照1组、对照2组及治疗组，每组28例。对照1组予基础治疗，对照2组在对照1组基础上予中医走罐疗法，治疗组在对照1组基础上予疏肝解郁汤联合中医走罐疗法。比较3组患者治疗前后中医证候积分、影像学指标、内分泌代谢指标，并评价疗效，观察不良反应。结果：总有效率治疗组为92.86%（26/28），对照1组为10.71%（3/28），对照2组为71.43%（20/28），治疗组高于对照1、2组（P＜0.05），对照2组高于对照1组（P＜0.05）。治疗后，治疗组及对照2组患者中医证候积分均低于治疗前（P＜0.05），且治疗组低于对照2组及对照1组（P＜0.05），对照2组低于对照1组（P＜0.05）。治疗后，治疗组及对照2组患者结节体积及最大直径小于治疗前（P＜0.05），且治疗组小于对照2组及对照1组（P＜0.05），对照2组小于对照1组（P＜0.05）。治疗后，治疗组及对照2组患者血清游离甲状腺素（FT4）、游离三碘甲状腺原氨酸（FT3）含量高于治疗前（P＜0.05），血清促甲状腺素（TSH）含量低于治疗前（P＜0.05），且治疗组患者血清FT4、FT3含量高于对照2组及对照1组（P＜0.05）、血清TSH含量低于对照2组及对照1组（P＜0.05），对照2组患者血清FT4、FT3含量高于对照1组（P＜0.05）、血清TSH含量低于对照1组（P＜0.05）。3组患者不良反应发生率比较，差异无统计学意义（P＞0.05）。结论：疏肝解郁汤联合中医走罐疗法治疗甲状腺结节具有较好疗效，能减轻症状，改善甲状腺影像学指标，促进内分泌代谢恢复。

关键词：甲状腺结节；疏肝解郁汤；中医走罐疗法；代谢指标

Abstract：Objective: To investigate the curative effect of Shugan Jieyu Decoction combined with moving cupping therapy on thyroid nodules. Methods: Eighty-four patients with thyroid nodules were divided into control group 1, control group 2, and treatment group using a random number table, with 28 cases in each group. Control group 1 received basic treatment, control group 2 received moving cupping therapy in addition to the basic treatment of control group 1, and the treatment group received Shugan Jieyu Decoction combined with moving cupping therapy in addition to the basic treatment of control group 1. The TCM syndrome scores, imaging indicators, endocrine and metabolic indicators were compared among the three groups before and after treatment. The curative effect was evaluated, and adverse reactions were observed. Results: The total effective rate was 92.86% (26/28) in the treatment group, 10.71% (3/28) in control group 1 and 71.43% (20/28) in control group 2. The total effective rate of the treatment group was higher than that of control group 1 and control group 2 (P<0.05); the total effective rate of control group 2 was higher than that of control group 1 (P<0.05). After treatment, the TCM syndrome scores in the treatment group and control group 2 were lower than those before treatment (P<0.05). The TCM syndrome score of the treatment group was lower than those of control group 2 and control group 1 (P<0.05), and the score of control group 2 was lower than that of control group 1 (P<0.05). After treatment, the nodule volume and maximum diameter in the treatment group and control group 2 were smaller than those before treatment (P<0.05). The nodule volume and maximum diameter in the treatment group were smaller than those in control group 2 and control group 1 (P<0.05), and those in control group 2 were smaller than those in control group 1 (P<0.05). After treatment, the serum levels of free thyroxine (FT4) and free triiodothyronine (FT3) in the treatment group and control group 2 were higher than those before treatment (P<0.05), while the serum TSH level was lower than before treatment (P<0.05). The serum FT4 and FT3 levels in the treatment group were higher than those in control group 2 and control group 1 (P<0.05), and the serum TSH level was lower than those in control group 2 and control group 1 (P<0.05). The serum FT4 and FT3 levels in control group 2 were higher than those in control group 1 (P<0.05), and the serum TSH level was lower than that in control group 1 (P<0.05). There was no statistically significant difference in the incidence of adverse reactions among the three groups (P>0.05). Conclusion: Shugan Jieyu Decoction combined with moving cupping therapy has a good curative effect on thyroid nodules. It can alleviate symptoms, improve thyroid imaging indicators, and promote the recovery of endocrine metabolism.

Key words：thyroid nodule; Shugan Jieyu Decoction; moving cupping therapy; metabolic indicators

发布时间：2025-11-30

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