乳腺癌中医药研究现状、热点与趋势分析*

作者：杨 娟1，全 佳2，陈红涛2

单位：1.湖南中医药大学第一附属医院，湖南 长沙 410007； 2.湖南中医药大学，湖南 长沙 410208

引用：引用：杨娟，全佳，陈红涛.乳腺癌中医药研究现状、热点与趋势分析[J].中医药导报,2026,32(5):242-248.

DOI：10.13862/j.cn43-1446/r.2026.05.037

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摘要：

目的：基于科学知识图谱CiteSpace对乳腺癌中医药研究的现状、热点与趋势进行文献计量学及可视化分析。方法：以中国知网（CNKI）和万方数据知识服务平台（Wanfang Data）中北大中文核心期刊和CSCD来源期刊的文献数据为资料来源，采用高级检索，检索时限为1990年1月1日至2025年10月30日。设定文献筛选标准，将纳入文献采用CiteSpace 5.8.R3软件生成发文作者（author）、研究机构（institution）、关键词（keyword）节点所对应的知识图谱。结果：CNKI共纳入文献497篇，Wanfang Data共纳入文献492篇，经过去重处理和人工筛选后得到712篇文献作为样本数据进行研究。分析结果显示，乳腺癌中医药研究发文量呈逐步增长趋势，可划分为起步探索期（1990—2000年）、稳步增长期（2001—2012年）、规模化发展期（2013—2019年）及爆发增长期（2020—2025年）4个阶段。该领域形成了以司徒红林、刘胜、陆德铭、林毅、王笑民等为代表的作者合作群，网络规模较大，发文量较高，为该领域的核心研究团队，且团队间有一定的合作关系。涉及514家机构，发文量≥10篇的机构有19家，其中上海中医药大学附属龙华医院发文量最高（51篇），广东省中医院次之（46篇），机构合作网络共现知识图谱中形成了以上海、北京、广东为核心的三大区域网络，体现中医药资源的区域集中性。研究聚焦中医传统优势、中西医结合、细胞分子机制、现代技术融合四大核心方向；呈现从疾病治疗到全周期健康管理、从广泛干预到精准靶向、从单一疗法到多手段协同的发展趋势，与世界卫生组织（WHO）全球乳腺癌倡议（GBCI）核心目标高度契合。结论：本研究通过可视化图谱揭示了该领域的学术网络、研究热点与发展规律，可为乳腺癌中医药的临床应用、科研创新及国际化发展提供参考。

关键词：乳腺癌；中医药；CiteSpace；文献计量；可视化分析

Abstract：

Objective: To conduct a bibliometric and visual analysis of the current status, hotspots, and trends of traditional Chinese medicine (TCM) research on breast cancer based on the scientific knowledge mapping tool CiteSpace. Methods: Literature data were retrieved from Peking University Chinese Core Journals and CSCD-source journals in the China National Knowledge Infrastructure (CNKI) and Wanfang Data Knowledge Service Platform (Wanfang Data) via advanced search, covering the period from January 1, 1990, to October 30, 2025. After applying literature screening criteria, CiteSpace 5.8.R3 was used to construct knowledge maps for authors, institutions, and keywords. Results: A total of 497 literatures were included from CNKI and 492 from Wanfang Data. After deduplication and manual screening, 712 literatures were selected as sample data for the study. The analysis showed that the number of publications on TCM research of breast cancer presented a gradual growth trend, which could be divided into four stages: initial exploration stage (1990-2000), steady growth stage (2001-2012), large-scale development stage (2013-2019), and explosive growth stage (2020-2025). The field has formed core author collaboration groups represented by SITU Honglin, LIU Sheng, LU Deming, LIN Yi, WANG Xiaomin, and etc., with large network scales and high publication volumes. These groups are the core research teams in the field and have certain collaborative relationships among them. A total of 514 institutions were involved, among which 19 institutions published ≥10 papers. Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine had the highest number of publications (51 papers), followed by Guangdong Provincial Hospital of Chinese Medicine (46 papers). The co-occurrence knowledge graph of institutional collaboration networks formed three core regional networks centered in Shanghai, Beijing, and Guangdong, reflecting the regional concentration of TCM resources. The research focuses on four core directions: traditional advantages of TCM, integration of Chinese and western medicine, cellular and molecular mechanisms, and integration of modern technologies. It presents development trends from disease treatment to full-cycle health management, from extensive intervention to precision targeting, and from single therapy to multi-method synergy, which are highly consistent with the core objectives of the WHO Global Breast Cancer Initiative (GBCI). Conclusion: This study reveals the academic network, research hotspots, and development rules in the field through visual graphs, which can provide references for the clinical application, scientific research innovation, and international development of TCM in breast cancer.

Key words：breast cancer; traditional Chinese medicine; CiteSpace; bibliometrics; visual analysis

发布时间：2026-05-24

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