中医药联合雄激素剥夺治疗前列腺癌研究进展*

作者：李晓芹，黄志成，张桂豪

单位：梅州市人民医院（黄塘医院），广东 梅州 514031

引用：引用：李晓芹，黄志成，张桂豪.中医药联合雄激素剥夺治疗前列腺癌研究进展[J].中医药导报,2026,32(5):137-141,156.

DOI：10.13862/j.cn43-1446/r.2026.05.022

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摘要：针对前列腺癌的中医病因病机、辨证论治及中医药联合雄激素剥夺（ADT）治疗的研究进行综述。前列腺癌的主要病机在于内外因综合作用致机体本虚标实，代谢失常，形成瘀血、痰浊、湿热等病理产物，日久酿生癌邪而发病，其中本虚为正气不足、肾气亏虚、阳气虚衰，标实为瘀血、痰浊、湿热、癌毒。ADT是临床治疗前列腺癌的核心手段，但易引发骨质疏松等并发症，治疗时需基于整体观及辨证论治原则，联用中医药可增效减毒、缓解症状，以改善患者预后及生存质量。

关键词：前列腺癌；中医药；雄激素剥夺治疗；综述

Abstract：

This article reviews the research on the etiology and pathogenesis of prostate cancer in traditional Chinese medicine (TCM), syndrome differentiation and treatment, and TCM combined with androgen deprivation therapy (ADT). The main pathogenesis of prostate cancer lies in the combined action of internal and external factors, leading to a condition of root deficiency and branch excess, metabolic disorders, and the formation of pathological products such as blood stasis, phlegm turbidity, and dampness-heat. Over time, these factors give rise to cancer. The root deficiency includes deficiency of healthy qi, kidney qi deficiency, and yang qi deficiency, while the branch excess includes blood stasis, phlegm turbidity, dampness-heat, and cancer toxin. ADT is a core method in the clinical treatment of prostate cancer, but it is prone to complications such as osteoporosis. Treatment should be based on the principles of holistic view and syndrome differentiation. The combination of TCM and ADT can enhance efficacy, reduce toxicity, and alleviate symptoms, thereby improving patient prognosis and quality of life.

Key words：prostate cancer; traditional Chinese medicine; androgen deprivation therapy; review

发布时间：2026-05-23

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