基于伏邪理论探讨复发性银屑病的防治与管理*

作者：周兢兢1，覃叶萍1，王艾琳1，李东东2

单位：1.重庆中医药学院附属第一医院，重庆 400011； 2.黑龙江中医药大学，黑龙江 哈尔滨 150000

引用：引用：周兢兢，覃叶萍，王艾琳，李东东.基于伏邪理论探讨复发性银屑病的防治与管理[J].中医药导报,2025,31(10):55-58,68.

DOI：10.13862/j.cn43-1446/r.2025.10.009

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摘要：复发性银屑病迁延反复的病程特点与其“潜伏待发”的病理机制密切相关。伏邪理论揭示了邪气潜藏、正虚为本、感而易发的机制，与现代免疫学中组织常驻记忆性T细胞（TRM）介导的免疫记忆、促炎因子持续激活机制高度契合。基于伏邪理论，本文构建了涵盖潜伏期、高危期及发作期的阶段性干预体系，并提出扶正祛邪、内外兼顾、多维调控的中西医结合防治模式。通过融合中医辨证论治与现代生物制剂、人工智能技术，形成以TRM调控为靶点的个体化管理方案，为复发性银屑病的精准防控提供了理论依据与实践路径。

关键词：银屑病；伏邪理论；复发机制；慢病管理

Abstract：

The characteristics of the prolonged and recurrent course of recurrent psoriasis are closely related to its pathological mechanism of "latent onset". The theory of suppressing evil reveals the mechanism of hidden evil qi, deficiency of positive energy as the foundation, and susceptibility to infection, which is highly consistent with the immune memory mediated by tissue resident memory T cells (TRM) and the sustained activation mechanism of pro-inflammatory factors in modern immunology. Based on the theory of suppressing evil, this article constructs a phased intervention system that covers the latent period, high-risk period, and attack period, and proposes a combination of traditional Chinese and Western medicine prevention and treatment model that supports the body and eliminates evil, balances internal and external factors, and multi-dimensional regulation. By integrating traditional Chinese medicine syndrome differentiation and treatment with modern biological agents and artificial intelligence technology, an individualized management plan targeting TRM regulation has been formed, providing theoretical basis and practical path for precise prevention and control of recurrent psoriasis.

Key words：psoriasis; Fuxie theory; recurrence mechanism; chronic disease management

发布时间：2026-01-08

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