白头翁汤及其加减方治疗溃疡性结肠炎的作用机制研究进展*

作者：刘翠翠1，崔 西1，柳芹芹1，赵高斯2，史树勋2

单位：1.甘肃中医药大学，甘肃 兰州 730000； 2.甘肃中医药大学附属医院，甘肃 兰州 730000

引用：引用：刘翠翠，崔西，柳芹芹，赵高斯，史树勋.白头翁汤及其加减方治疗溃疡性结肠炎的作用机制研究进展[J].中医药导报,2025,31(5):166-171.

DOI：10.13862/j.cn43-1446/r.2025.05.029

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摘要：综述白头翁汤及其加减方治疗溃疡性结肠炎（UC）的各种作用机制。白头翁汤可能通过多靶点、多途径和多机制缓解肠道炎症，恢复结肠黏膜正常结构及功能，达到治愈UC的目的。作用机制主要包括调节机体免疫功能、调节细胞因子、调控细胞信号通路、抑制氧化应激反应、调节肠道菌群及修复肠黏膜屏障、调节凝血功能。

关键词：溃疡性结肠炎；白头翁汤；作用机制；综述

Abstract：

This paper reviews various mechanisms of Baitouweng Tang and its modified formulas in treating ulcerative colitis (UC). Baitouweng Tang may relieve intestinal inflammation through multiple targets, multiple pathways, and multiple mechanisms, restore the normal structure and function of the colonic mucosa, and achieve the goal of curing UC. The mechanisms mainly include regulating the immune function of the body, regulating cytokines, regulating cell signaling pathways, inhibiting oxidative stress response, regulating the intestinal flora, repairing the intestinal mucosal barrier, and regulating the coagulation function.

Key words：ulcerative colitis; Baitouweng Tang; action mechanism; review

发布时间：2025-12-31

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