基于隐结构模型分析宋虎杰治疗小儿脑瘫的辨证规律*
作者：宋文娟1，王 兴2，宋虎杰2，杜晓刚2
单位：1.陕西中医药大学，陕西 西安 712046； 2.陕西中医药大学附属西安中医脑病医院，陕西 西安 710032
引用：引用：宋文娟，王兴，宋虎杰，杜晓刚.基于隐结构模型分析宋虎杰治疗小儿脑瘫的辨证规律[J].中医药导报,2025,31(11):184-189.
DOI：10.13862/j.cn43-1446/r.2025.11.031
PDF：
下载PDF
摘要：
目的：基于隐结构模型分析宋虎杰教授治疗小儿脑瘫的辨证规律。方法：收集2023年1月至2024年3月在陕西中医药大学附属西安中医脑病医院住院，并由宋虎杰教授指导治疗的脑瘫患儿的病历资料。资料经过预处理后，运用孔明灯Lantern 5.0软件，并选定双步隐树分析算法构建针对患儿症状特征的隐结构模型，综合考量互信息、信息覆盖率等核心指标，结合相关中医理论知识对模型进行人工诠释。并进行综合聚类分析，以揭示宋虎杰教授治疗小儿脑瘫的辨证规律，并尝试建立宋虎杰教授小儿脑瘫辨证的客观定量标准。结果：纳入301份脑瘫患儿病历，共110个显变量（包含症状、舌象、脉象）构建隐结构模型，模型总计有13个隐变量、29个隐类、5个综合聚类。结论：小儿脑瘫的病位主要涉及肝、脾、肾、心及脑窍，病理因素以正虚、阳亢、痰瘀为主，主要证候包括脾虚肝亢证、痰瘀阻滞证、心脾两虚证、脾肾虚弱证、肝肾亏损证。
关键词：隐结构模型；小儿脑瘫；辨证规律；证候；宋虎杰
Abstract：
Objective: To explore the syndrome differentiation rules of professor SONG Hujie in the treatment of cerebral palsy in children based on the latent structure model. Methods: The medical records of children with cerebral palsy treated under the guidance of professor SONG Hujie from January 2023 to March 2024 at Xi'an Traditional Chinese Medicine Encephalopathy Hospital affiliated to Shaanxi University of Chinese Medicine were collected. After preprocessing the data, the Lantern 5.0 software was used to construct a latent structure model of symptoms using the BI algorithm. Comprehensive consideration was given to key parameters such as mutual information and information coverage for manual model interpretation and comprehensive cluster analysis. The aim was to reveal the syndrome differentiation rules of professor SONG Hujie in the treatment of cerebral palsy in children and attempt to establish an objective quantitative standard for syndrome differentiation of cerebral palsy in children by professor SONG Hujie. Results: A total of 301 medical records of children with cerebral palsy were included, with 110 manifest variables (including symptoms, tongue manifestations, and pulse manifestations) used to construct the latent structure model. Subsequently, 13 latent variables, 29 latent classes, and 5 comprehensive cluster models were obtained. Conclusion: The disease locations of cerebral palsy in children mainly involve the liver, spleen, kidney, heart, and brain. The pathological factors are mainly deficiency of healthy Qi, hyperactivity of Yang, and phlegm-blood stasis. The main syndromes include spleen deficiency and liver hyperactivity syndrome, liver and kidney deficiency syndrome, spleen and kidney weakness syndrome, heart and spleen deficiency syndrome, and phlegm-blood stasis obstruction syndrome.
Key words：latent structure model; cerebral palsy in children; syndrome differentiation rules; syndromes; SONG Huijie
发布时间：2025-11-30
点击量：63