构建代谢相关脂肪性肝病人群调态打靶、限能和助推综合干预的减重管理模式*

作者:王景芝1,2,3,肖明中1,2,3,高小莲3,4,陶军秀1,2,3,向 聪4,罗燕玲4,欧阳卡妮1,2,3,鲁利碧1,2,3

单位:1.湖北省中医院/肝病研究所、中医肝肾研究及应用湖北省重点实验室,湖北 武汉 430061; 2.湖北中医药大学附属医院,湖北 武汉 430061; 3.湖北时珍实验室,湖北 武汉 430065; 4.湖北中医药大学护理学院,湖北 武汉 430070

引用:引用:王景芝,肖明中,高小莲,陶军秀,向聪,罗燕玲,欧阳卡妮,鲁利碧.构建代谢相关脂肪性肝病人群调态打靶、限能和助推综合干预的减重管理模式[J].中医药导报,2025,31(11):101-105,115.

DOI:10.13862/j.cn43-1446/r.2025.11.018

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摘要:

肥胖是代谢相关脂肪性肝病(MAFLD)的重要危险因素。本研究基于MAFLD“分类-分期-分证”框架,提出“调态打靶”中医干预策略,结合限能(中医辅助禁食疗法)与饮食管理助推技术(决策信息、决策辅助及决策结构影响),构建综合减重干预方案。该模式对改善MAFLD患者代谢状况效果明显,可为中医健康管理实践提供理论参考与方法支持。

关键词:代谢相关脂肪性肝病;调态打靶;限能干预;助推;减重管理

Abstract:

Obesity is an important risk factor for metabolic dysfunction-associated fatty liver disease (MAFLD). Based on the MAFLD "classification-staging-syndrome differentiation" framework, this study proposes a Traditional Chinese Medicine intervention strategy termed "state-target adjustment", combined with energy restriction (TCM-assisted fasting therapy) and dietary management nudging techniques (decision information, decision support, and decision structure influence), to construct a comprehensive weight loss intervention program. This model demonstrates significant effects in improving the metabolic status of MAFLD patients and can provide theoretical reference and methodological support for TCM-based health management practices.

Key words:metabolic dysfunction-associated fatty liver disease; state-target adjustment; energy restriction; nudging; weight management

发布时间:2025-11-30

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